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Differin (Adapalene) 0.1% information
Apply a thin layer of gel evenly over the acne affected areas only once daily at bedtime. Do not apply near or to the eyes, lips, nostrils or other sensitive areas. The gel should be applied to clean, dry skin and take care to wash your hands thoroughly before and after use.
Do not apply to broken skin.
Differin is a prescription only medicine and cannot be bought over the counter. If you are interested in this medicine, why not fill out our consultation questionnaire? This will be reviewed by one of our expert prescribers who will advise if this medicine is suitable and safe for you.
As with all medicines applied to the skin in the treatment of acne, you may not see results for up to eight weeks. It is important to be consistent in your application of this gel in order for it to work properly.
Differin is not suitable for those with a hypersensitivity to any of the ingredients. Do not use in pregnancy. Avoid sunlight and UV lamps while using this medicine. Do not use other acne products containing retinoids or benzoyl peroxide while using this medicine or products that are irritating, drying or exfoliating to the skin.
Some people can experience stinging sensation, dryness, scaling and burning sensitivity when they first use this medicine. This presents worst during the first week of use and then tends to settle.
Always read the patient information leaflet before commencing treatment.
View patient information leaflet.Differin is a gel that is used in the treatment of moderate to severe acne. It contains the active ingredients adapalene.
Adapalene belongs to a group of medicines called retinoids (which includes tretinoin) and helps to reduce inflammation and black and white head formation on the outer layer of the skin. Adapalene is an advanced third generation retinoid which exhibits many of the same effects as previous generation medicines like tretinoin but is often tolerated better.
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Backed by our experienced UK-based medical team
Dr Bryony Henderson
Dr. Bryony Henderson joins HeliosX as Medical Director for the UK and US, bringing extensive clinical operations, governance, and digital health experience from Kry/Livi and Numan. A recognised clinical voice, she has contributed to award-winning campaigns, published on health inequalities, and appeared across major national media. At HeliosX, she leads clinical governance and quality and supports the delivery of safe, innovative, scalable care.
Dr Adam Abbs
Adam is a doctor and advocate for increasing access to healthcare internationally. He has extensive experience in video consultations, technology-enabled examinations, remote biomarker testing, and education. He is a published author and has medical licenses in the UK, Spain and Republic of Ireland.
Dr Safia Hussain
Consultant GP and Quality Lead
MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology
Safia is a GP with experience working in the NHS with a particular interest in diabetes and weight loss management. She is passionate about the power of digital healthcare and oversees our approach to patient safety and regulatory compliance.
Declan Lismore
Declan is a pharmacist with 15 years of experience and is passionate about digital healthcare. He has extensive experience across all pharmacy sectors in the UK and Ireland. He has led the clinical and regulatory functions of some of the biggest pharmacy organisations in the UK and is excited about the future of the industry.